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The QCD running coupling $\alpha_s(Q^2)$ sets the strength of the interactions of quarks and gluons as a function of the momentum transfer $Q$.
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For a recent review see, A. Deur, S. J. Brodsky, G. F. de Teramond, The QCD running coupling (JLAB-PHY-16-2199, SLAC-PUB-16448, to be published in Prog. Nuc. Part. Phys. (2016)) and references within
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