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2007

Population stratification using a statistical model on hypergraphs

Vazquez, Alexei

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Population stratification is a problem encountered in several areas of biology and public health.

We tackle this problem by mapping a population and its elements attributes into a hypergraph, a natural extension of the concept of graph or network to encode associations among any number of elements.
On this hypergraph, we construct a statistical model reflecting our intuition about how the elements attributes can emerge from a postulated population structure.
Finally, we introduce the concept of stratification representativeness as a mean to identify the simplest stratification already containing most of the information about the population structure.

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