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Antibodies are widely used as therapeutics, but their development requires costly affinity maturation, involving iterative mutations to enhance binding affinity.This paper explores a sequence-only scenario for affinity maturation, using solely antibody and antigen sequences.
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Jing, B., Eismann, S., Suriana, P., Townshend, R. J. L., and Dror, R · 2021
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Ruffolo, J. A., Gray, J. J., and Sulam, J · 2021
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