Illuminate: A novel approach for depression detection with explainable analysis and proactive therapy using prompt engineering

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This paper introduces a novel paradigm for depression detection and treatment using advanced Large Language Models (LLMs): Generative Pre-trained Transformer 4 (GPT-4), Llama 2 chat, and Gemini.

• These LLMs are fine-tuned with specialized prompts to diagnose, explain, and suggest therapeutic interventions for depression.
• A unique few-shot prompting method enhances the models' ability to analyze and explain depressive symptoms based on the DSM-5 criteria.
• In the interaction phase, the models engage in empathetic dialogue management, drawing from resources like PsychDB and a Cognitive Behavioral Therapy (CBT) Guide, fostering supportive interactions with individuals experiencing major depressive disorders.