Multiplexed Immunofluorescence Brain Image Analysis Using Self-Supervised Dual-Loss Adaptive Masked Autoencoder

Understand

Reliable large-scale cell detection and segmentation is the fundamental first step to understanding biological processes in the brain.

• The ability to phenotype cells at scale can accelerate preclinical drug evaluation and system-level brain histology studies.
• The impressive advances in deep learning offer a practical solution to cell image detection and segmentation.
• Unfortunately, categorizing cells and delineating their boundaries for training deep networks is an expensive process that requires skilled biologists.