Region-specific Diffeomorphic Metric Mapping

Understand

We introduce a region-specific diffeomorphic metric mapping (RDMM) registration approach.

• RDMM is non-parametric, estimating spatio-temporal velocity fields which parameterize the sought-for spatial transformation.
• Regularization of these velocity fields is necessary.
• However, while existing non-parametric registration approaches, e.g., the large displacement diffeomorphic metric mapping (LDDMM) model, use a fixed spatially-invariant regularization our model advects a spatially-varying regularizer with the estimated velocity field, thereby naturally attaching a spatio-temporal regularizer to deforming objects.