Computer aided detection of tuberculosis on chest radiographs: An evaluation of the CAD4TB v6 system

Understand

There is a growing interest in the automated analysis of chest X-Ray (CXR) as a sensitive and inexpensive means of screening susceptible populations for pulmonary tuberculosis.

• In this work we evaluate the latest version of CAD4TB, a commercial software platform designed for this purpose.
• Version 6 of CAD4TB was released in 2018 and is here tested on a fully independent dataset of 5565 CXR images with GeneXpert (Xpert) sputum test results available (854 Xpert positive subjects).
• A subset of 500 subjects (50% Xpert positive) was reviewed and annotated by 5 expert observers independently to obtain a radiological reference standard.