Accelerated Reconstruction of Perfusion-Weighted MRI Enforcing Jointly Local and Nonlocal Spatio-temporal Constraints

Understand

Perfusion-weighted magnetic resonance imaging (MRI) is an imaging technique that allows one to measure tissue perfusion in an organ of interest through the injection of an intravascular paramagnetic contrast agent (CA).

• Due to a preference for high temporal and spatial resolution in many applications, this modality could significantly benefit from accelerated data acquisitions.
• In this paper, we specifically address the problem of reconstructing perfusion MR image series from a subset of k-space data.
• Our proposed approach is motivated by the observation that temporal variations (dynamics) in perfusion imaging often exhibit correlation across different spatial scales.