Alignment of metabolic trajectories with application to metabonomic toxicology

Understand

Geometry of the metabolic trajectories is characteristic of the biological response (Keun, Ebbels et al.

• 2004).
• Yet, due to unavoidable inter-individual variations, the exact trajectories characterising the biological responses differ.
• We examined whether the differences seen between metabolic trajectories of a specific treatment, correspond to the variations seen in the other biological manifestations of the same treatment.